- The most common cause of sudden cardiac death in adults
over the age of 40 has been coronary artery atheroma seen in postmortem
examination in about 100 cases randomly selected by me in the mortuary of
AIIMS.
- The most common finding at postmortem examination is
chronic high-grade stenosis of minimum one segment of a major coronary
artery, the arteries which supply the heart muscle with its blood supply.
A significant number of cases also have an identifiable clot in a major
coronary artery which causes transmural occlusion of that vessel.
- In 75 out of hundred cases, the clot was found in the
right coronary artery supplying the electrical area of heart. Death in
these cases is thought to result from a period of transient or prolonged
lack of blood supply in the muscle of the heart wall, which induces a
ventricular arrhythmia/fibrillation and no changes in the myocardium are
seen during postmortem examination.
- The absence of the histological signs of acute necrosis
and a healed infarct are a common finding.
- Chronic high–grade stenosis causing previous episodes of
ischemia and areas of focal fibrosis is seen histologically in the
myocardium.
- Ventricular arrhythmias may arise from a myocardium
which has been previously scarred by episodes of ischemia.
Tuesday, 19 March 2013
Emedinews:Insights on Medicolegal Issues:Right coronary artery supplying blood to the electrical area of heart is called artery of sudden death
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