Vitamin may have no role in hypertension

Supplementation with high doses of oral vitamin D3 every 3 months did not have a significant effect on blood pressure in older patients with isolated systolic hypertension as per a small randomized trial reported online in JAMA Internal Medicine. At both 3 months and 1 year, there were no differences in office blood pressure between the supplementation and placebo groups. And there were no effects seen on nearly all of the secondary outcomes, with the exception of parathyroid hormone levels, which dropped by 3.8 ng/mL with supplementation relative to placebo.