• Plasma can be donated much more frequently than whole blood donation even up to twice a week. This is because the red blood cells, which take so much time to replace, are separated from the plasma and injected back into the plasma donor in saline solution.
• Whole blood refers to blood that contains all its components, including red blood cells, white blood cells, platelets, and so on. "Plasma" can refer either to the yellowish fluid of blood in which the cells are suspended, or to the blood after RBCs have been removed.
• In cases of Donor and Recipient mismatch, the plasma can be given to a recipient with an incompatible group much more safely than RBCs, since the antibodies in the plasma are quickly diluted when transfused into circulatory system
• In case of trauma/serious injuries resulting in massive ongoing blood loss, the plasma can be transfused to restore the volume of the recipient's blood and to stop bleeding because of its high concentration of clotting factors. Hemophiliacs, who don't clot well, are frequent recipients of plasma.
• Whole blood is rarely used and medically required for transfusions. Rare exceptions are for sickle cell disease and heart surgery, in which the blood loss can be several units.
• RBCs have blood group antigens that cause illness and even death has been known to occur on several occasions when types are mismatched. Plasma contains antibodies for the antigens proteins in red blood cells that trigger an immune response.
(Dr Sudhir Gupta, Additional Prof, Forensic Medicine & Toxicology, AIIMS)
• Whole blood refers to blood that contains all its components, including red blood cells, white blood cells, platelets, and so on. "Plasma" can refer either to the yellowish fluid of blood in which the cells are suspended, or to the blood after RBCs have been removed.
• In cases of Donor and Recipient mismatch, the plasma can be given to a recipient with an incompatible group much more safely than RBCs, since the antibodies in the plasma are quickly diluted when transfused into circulatory system
• In case of trauma/serious injuries resulting in massive ongoing blood loss, the plasma can be transfused to restore the volume of the recipient's blood and to stop bleeding because of its high concentration of clotting factors. Hemophiliacs, who don't clot well, are frequent recipients of plasma.
• Whole blood is rarely used and medically required for transfusions. Rare exceptions are for sickle cell disease and heart surgery, in which the blood loss can be several units.
• RBCs have blood group antigens that cause illness and even death has been known to occur on several occasions when types are mismatched. Plasma contains antibodies for the antigens proteins in red blood cells that trigger an immune response.
(Dr Sudhir Gupta, Additional Prof, Forensic Medicine & Toxicology, AIIMS)
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