Monday, 5 December 2011

Emedinews:Makesure:A hypertensive with obstructive sleep apnea (OSA) was not responding to CPAP.

Situation: A hypertensive with obstructive sleep apnea (OSA) was not responding to CPAP.
Reaction: Oh my God! Why was an antihypertensive drug not started?
Lesson: Make sure that all hypertensives with OSA are given anti-HT drugs in addition to CPAP. In a randomized crossover trial of 23 patients with OSA and systemic hypertension, an anti-hypertensive medication (valsartan 160 mg/day) lowered the mean 24-hour blood pressure significantly more than CPAP (Continuous positive airway pressure therapy) therapy alone in untreated hypertensive patients with OSA. (Am J Respir Crit Care Med 2010;182(7):954-60).

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