Children at risk of future obesity should be examined for body mass index (BMI) rebound.
BMI rebound is the age at which body mass index (BMI) reaches its lowest point before increasing through later childhood, adolescence and adulthood.
An earlier BMI rebound age is associated with adverse risk factors for heart disease as measured at age 7: higher BMI, higher systolic and diastolic blood pressures, higher serum insulin and leptin levels, higher left ventricular mass and left atrial size.
Early BMI rebound age for children is lower than 4.4 years for boys and 4.2 years for girls. The normal values are 4.4 to 6.6 years for boys and 4.2 to 5.7 years for girls.
All children who start gaining weight between 3-4 years should be classified as a high risk for future diabetes and heart disease.